Cohen and Hersh Briefings in Bioinformatics 2005

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Citation

Aaron M. Cohen and William R. Hersh. 2005. A Survey of Current Work in Biomedical Text Mining. Briefings in Bioinformatics. Vol 6. No 1. 57-71.

Online version

oxfordjournals

Summary

This is a survey paper about biomedical text mining in 2005.

  • Named entity recognition
    • Problems
      • No complete dictionary for most types of biological named entities
      • ambiguous words and phrases
      • multi names
    • approaches are mainly categorized into three below
      • lexicon based
      • rule based
      • statistically based
    • performance
      • overall, the performance of gene and protein NER systems is F-scores between 75 and 85 percent.
  • Text classification


  • Synonym and abbreviation extraction
    • Synonym
      • use dictionary
      • automatic extraction of gene name synonyms from biomedical free text
      • SVM classifier-based
      • pattern-based
    • abbreviation
      • either the full form or the abbreviation is often enclosed in parentheses.
      • a variety of alignment and scoring methods
  • Relationship extraction
    • detect occurrences of a prespecified type of relationship between a pair of entities of given types
    • manually generated template-based methods
    • automatic template methods
    • statistical methods
    • NLP-based methods

mostly are about the relationships between genes and proteins

  • Hypothesis generation
    • uncover relationships that are not present in the text but instead are inferred by the presence of other more explicit relationships. uncover previously unrecognized relationships
  • Integration frameworks
    • integrated text-mining frameworks
    • still in the research and development phrase.
  • The authors' suggestions
    • Access to full text is required
    • Additional analytical methods with possible features are required for a particular application
    • Researchers should consider actual users' needs. The performance of a system with certain metrics does not guarantee users' satisfaction.
    • Shared challenge tasks should be continued